Automated brain MRI metrics in the EPIRMEX cohort of preterm newborns: Correlation with the neurodevelopmental outcome at 2 years

The purpose of this study was to identify in the EPIRMEX cohort correlations between MRI brain metrics, including diffuse excessive high signal intensities (DEHSI) obtained with an automated quantitative method and neurodevelopmental outcomes at 2 years. A total 390 very preterm infants (gestational age birth ≤ 32 weeks) who underwent term equivalent 1.5T (n = 338) or 3T 52) were prospectively included. Using a validated algorithm, metrics main surfaces (cortical deep gray matter, white cerebrospinal fluid) DEHSI three thresholds obtained. Linear adjust regressions performed assess correlation ages stages questionnaire (ASQ) score Basal ganglia thalami, cortex matter positively significantly correlated global ASQ score. For all sub-domains, basal thalami scores. present 289 premature newborns (74%) without any Metrics greater than 1.5T. Brain our multicentric correlate outcome years age. detection is not predictive adverse outcomes. Our algorithm might easily provide useful information daily practice.